In this role, Dr.
References Ovarian cancer is the most lethal gynecologic cancer. Less than one-half of patients survive for more than five years after diagnosis. Ovarian cancer affects women of all ages but is most commonly diagnosed after menopause. The strongest risk factors are advancing age and family history of ovarian and breast cancer.
Women who have symptoms concerning for ovarian cancer should undergo a physical examination, transvaginal ultrasonography, and measurement of biomarkers such as cancer antigen If results are suspicious for ovarian cancer, the patient should be referred to a gynecologic oncologist.
Despite the low rate of early diagnosis, guidelines recommend against routine screening for ovarian cancer in average-risk women because screening, including routine pelvic examinations, is ineffective and associated with harm. However, a recent trial found a potential benefit of annual screening using an algorithm based on serial cancer antigen measurements followed by transvaginal ultrasonography for women at increased risk, as determined by the algorithm.
Women with an increased-risk family history should be referred for genetic counseling and, if genetic mutations e. The treatment of ovarian cancer usually involves surgery, with or without intraperitoneal and intravenous chemotherapy.
Primary care physicians have important roles in posttreatment surveillance and end-of-life care. Ovarian cancer is the most lethal gynecologic cancer.
It affects women of all ages, but is most commonly diagnosed in those 55 to 64 years of age. American College of Obstetricians and Gynecologists Do not screen low-risk women with cancer antigen CA or ultrasound for ovarian cancer. Society of Gynecologic Oncology Source: For more information on the Choosing Wisely Campaign, see http: For supporting citations and to search Choosing Wisely recommendations relevant to primary care, see https: A The American College of Physicians recommends against routine screening pelvic examinations in asymptomatic women.
Preventive Services Task Force.
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